Não há consenso na literatura avaliada sobre os fatores relacionados ao desenvolvimento de fraturas, sendo a dose de radiação, o tamanho prévio do tumor e o descolamento periosteal sugeridos como fatores potenciais.įraturas espontâneas Consolidação da fratura Radioterapia Efeitos de radiação A etiologia ainda é incerta, mas foram observados desaparecimento celular, redução do turnover ósseo e da atividade hematopoiética como possíveis causas da falha de consolidação. Os fatores de risco incluem idade acima de 50 anos, sexo feminino, descolamento periosteal extenso, irradiação circunferencial, tamanho do tumor e localização anterior na coxa. O tempo decorrido entre a irradiação e a fratura ocorre anos após a radioterapia. RESULTADOS:Ī incidência de fraturas após irradiação varia de 1,2% a 25% com taxa de consolidação de 33% a 75%, sendo mais frequente em costelas, pelve e fêmur. Identificação de publicações sobre as fraturas patológicas ocorridas em esqueleto previamente exposto à radiação ionizante. There is no consensus in the literature on the factors related to the development of fractures, with radiation dose, previous tumor size and periosteal detachment being suggested as potential factors.įractures, Spontaneous Fracture Healing Radiotherapy Radiation EffectsĪvaliar dados epidemiológicos e tratamentos disponíveis para fraturas secundárias ao tratamento radioterápico. The etiology is still uncertain, but cellular disappearance, reduction of bone turnover and activity were observed hematopoietic as possible causes of failure of consolidation. Risk factors include age above 50 years, female gender, extensive periosteal detachment, circumferential irradiation, tumor size, and anterior thigh location. The time elapsed between irradiation and fracture occurs years after radiotherapy. The incidence of fractures after irradiation varies from 1.2% to 25% with a consolidation rate of 33% to 75%, being more frequent in the ribs, pelvis, and femur. Identification of publications on pathological skeletal fractures previously exposed to ionizing radiation. The case suggests that focal osteolytic lesions of the ribs may regress over time and become scintigraphically inactive.To evaluate the epidemiological data and available treatments for fractures secondary to radiotherapy treatment. We conclude that osteoporosis should be included in the differential diagnosis of asymptomatic focal osteolysis of the ribs with rib fractures as a complication of acute cough. Five years later radiological and bone scintigraphy revealed resolution of the lesion. The patient was observed between the year 20. Pharmacomedical treatments for osteoporosis were applied. Final diagnosis was based on plain radiography, bone scan and bone densitometry. The authors describe multiple focal osteolytic lesions with rib fractures appearing in a pattern that could be confused with metastases. The diagnosis had to be approached as a diagnosis of exclusion since known causes of the osteolytic process had to be eliminated. The lesions were detected by chance after acute cough-induced rib fractures were seen on plain chest radiographs.
![pathological fracture pathological fracture](http://radsource.us/wp-content/uploads/2012/04/3a.jpg)
This paper reports on a unique, previously unreported, successful outcome in the case of a patient with focal osteolytic lesions of the ribs as a first sign of osteoporosis.